1 Beta Release 0.1.2 (28 January, 2008)
2 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
4 Notable changes in SAMtools:
6 * Implemented a Bayesian indel caller. The new caller generate scores
7 and genotype and is potentially more accurate than Maq's indel
8 caller. The pileup format is also changed accordingly.
10 * Implemented rmdup command: remove potential PCR duplicates. Note that
11 this command ONLY works for FR orientation and requires ISIZE is
14 * Added fixmate command: fill in mate coordinates, ISIZE and mate
15 related flags from a name-sorted alignment.
17 * Fixed a bug in indexing: reads bridging 16x kbp were not retrieved.
19 * Allow to select reads shown in the pileup output with a mask.
21 * Generate GLFv2 from pileup.
23 * Added two more flags for flagging PCR/optical duplicates and for QC
26 * Fixed a bug in sort command: name sorting for large alignment did not
29 * Allow to completely disable RAZF (using Makefile.lite) as some people
30 have problem to compile it.
32 * Fixed a bug in import command when there are reads without
35 * Fixed a bug in tview: clipping broke the alignment viewer.
37 * Fixed a compiling error when _NO_CURSES is applied.
39 * Fixed a bug in merge command.
41 Changes in other utilities:
43 * Added wgsim, a paired-end reads simulator. Wgsim was adapted from
44 maq's reads simulator. Colin Hercus further improved it to allow
47 * Added wgsim_eval.pl, a script that evaluates the accuracy of
48 alignment on reads generated by wgsim.
50 * Added soap2sam.pl, a SOAP2->SAM converter. This converter does not
51 work properly when multiple hits are output.
53 * Added bowtie2sam.pl, a Bowtie->SAM converter. Only the top hit will
54 be retained when multiple hits are present.
56 * Fixed a bug in export2sam.pl for QC reads.
58 * Support RG tag at MAQ->SAM converter.
60 * Added novo2sam.pl, a NovoAlign->SAM converter. Multiple hits and
61 indel are not properly handled, though.
63 * Added zoom2sam.pl, a ZOOM->SAM converter. It only works with the
64 default Illumina output.
66 (0.1.2: 28 January 2008; r116)
70 Beta Release 0.1.1 (22 December, 2008)
71 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
73 The is the first public release of samtools. For more information,
74 please check the manual page `samtools.1' and the samtools website
75 http://samtools.sourceforge.net