Beta Release 0.1.2 (28 January, 2008) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Notable changes in SAMtools: * Implemented a Bayesian indel caller. The new caller generate scores and genotype and is potentially more accurate than Maq's indel caller. The pileup format is also changed accordingly. * Implemented rmdup command: remove potential PCR duplicates. Note that this command ONLY works for FR orientation and requires ISIZE is correctly set. * Added fixmate command: fill in mate coordinates, ISIZE and mate related flags from a name-sorted alignment. * Fixed a bug in indexing: reads bridging 16x kbp were not retrieved. * Allow to select reads shown in the pileup output with a mask. * Generate GLFv2 from pileup. * Added two more flags for flagging PCR/optical duplicates and for QC failure. * Fixed a bug in sort command: name sorting for large alignment did not work. * Allow to completely disable RAZF (using Makefile.lite) as some people have problem to compile it. * Fixed a bug in import command when there are reads without coordinates. * Fixed a bug in tview: clipping broke the alignment viewer. * Fixed a compiling error when _NO_CURSES is applied. * Fixed a bug in merge command. Changes in other utilities: * Added wgsim, a paired-end reads simulator. Wgsim was adapted from maq's reads simulator. Colin Hercus further improved it to allow longer indels. * Added wgsim_eval.pl, a script that evaluates the accuracy of alignment on reads generated by wgsim. * Added soap2sam.pl, a SOAP2->SAM converter. This converter does not work properly when multiple hits are output. * Added bowtie2sam.pl, a Bowtie->SAM converter. Only the top hit will be retained when multiple hits are present. * Fixed a bug in export2sam.pl for QC reads. * Support RG tag at MAQ->SAM converter. * Added novo2sam.pl, a NovoAlign->SAM converter. Multiple hits and indel are not properly handled, though. * Added zoom2sam.pl, a ZOOM->SAM converter. It only works with the default Illumina output. (0.1.2: 28 January 2008; r116) Beta Release 0.1.1 (22 December, 2008) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ The is the first public release of samtools. For more information, please check the manual page `samtools.1' and the samtools website http://samtools.sourceforge.net