+RSEM v1.2.14
+
+- Changed RSEM's behaviors for building Bowtie/Bowtie 2 indices. In 'rsem-prepare-reference', '--no-bowtie' and '--no-ntog' options are removed. By default, RSEM does not build either Bowtie or Bowtie 2 indices. Instead, it generates two index Multi-FASTA files, 'reference_name.idx.fa' and 'reference_name.n2g.idx.fa'. Compared to the former file, the latter one in addition converts all 'N's into 'G's. These two files can be used to build aligner indices for customized aligners. In addition, 'reference_name.transcripts.fa' does not have poly(A) tails added. To enable RSEM build Bowtie/Bowtie 2 indices, '--bowtie' or '--bowtie2' must be set explicitly. The most significant benefit of this change is that now we can build Bowtie and Bowtie 2 indices simultaneously by turning both '--bowtie' and '--bowtie2' on. Type 'rsem-prepare-reference --help' for more information
+- If transcript coordinate files are visualized using IGV, 'reference_name.idx.fa' should be imported as a genome (instead of 'reference_name.transcripts.fa'). For more information, see the third subsection of Visualization in 'README.md'
+- Modified RSEM perl scripts so that RSEM directory will be added in the beginning of the PATH variable. This also means RSEM will try to use its own samtools first
+- Added --seed option to set random number generator seeds in 'rsem-calculate-expression'
+- Added posterior standard deviation of counts as output if either '--calc-pme' or '--calc-ci' is set
+- Updated boost to v1.55.0
+- Renamed makefile as Makefile
+- If '--output-genome-bam' is set, in the genome BAM file, each alignment's 'MD' field will be adjusted to match the CIGAR string
+- 'XS:A:value' field is required by Cufflinks for spliced alignments. If '--output-genome-bam' is set, in the genome BAM file, first each alignment's 'XS' filed will be deleted. Then if the alignment is an spliced alignment, a 'XS:A:value' field will be added accordingly
+- Added instructions for users who want to put all RSEM executables into a bin directory (see Compilation & Installation section of 'README.md')
+
+--------------------------------------------------------------------------------------------
+
+RSEM v1.2.13
+
+- Allowed users to use the SAMtools in the PATH first and enabled RSEM to find its executables via a symbolic link
+- Changed the behavior of parsing GTF file. Now if a GTF line's feature is not "exon" and it does not contain a "gene_id" or "transcript_id" attribute, only a warning message will be produced (instead of failing the RSEM)
+
+--------------------------------------------------------------------------------------------
+
+RSEM v1.2.12
+
+- Enabled allele-specific expression estimation
+- Added '--calc-pme' option for 'rsem-calculate-expression' to calculate posterior mean estimates only (no credibility intervals)
+- Modified the shebang line of RSEM perl scripts to make them more portable
+- Added '--seed' option for 'rsem-simulate-reads' to enable users set the seed of random number generator used by the simulation
+- Modified the transcript extraction behavior of 'rsem-prepare-reference'. For transcripts that cannot be extracted, instead of failing the whole script, warning information is produced. Those transcripts are ignored
+
+--------------------------------------------------------------------------------------------
+
+RSEM v1.2.11
+
+- Enabled RSEM to use Bowtie 2 aligner (indel, local and discordant alignments are not supported yet)
+- Changed option names '--bowtie-phred33-quals', '--bowtie-phred64-quals' and '--bowtie-solexa-quals' back to '--phred33-quals', '--phred64-quals' and '--solexa-quals'
+
+--------------------------------------------------------------------------------------------
+
+RSEM v1.2.10
+
+- Fixed a bug which will lead to out-of-memory error when RSEM computes ngvector for EBSeq
+
+--------------------------------------------------------------------------------------------
+
+RSEM v1.2.9
+
+- Fixed a compilation error problem in Mac OS
+- Fixed a problem in makefile that affects 'make ebseq'
+- Added 'model_file_description.txt', which describes the format and meanings of file 'sample_name.stat/sample_name.model'
+- Updated samtools to version 0.1.19
+
+--------------------------------------------------------------------------------------------
+
+RSEM v1.2.8
+
+- Provided a more detailed description for how to simulate RNA-Seq data using 'rsem-simulate-reads'
+- Provided more user-friendly error message if RSEM fails to extract transcript sequences due to the failure of reading certain chromosome sequences
+
+--------------------------------------------------------------------------------------------
+
+RSEM v1.2.7
+
+- 'rsem-find-DE' is replaced by 'rsem-run-ebseq' and 'rsem-control-fdr' for a more friendly user experience
+- Added support for differential expression testing on more than 2 conditions in RSEM's EBSeq wrappers 'rsem-run-ebseq' and 'rsem-control-fdr'
+- Renamed '--phred33-quals', '--phred64-quals', and '--solexa-quals' in 'rsem-calculate-expression' to '--bowtie-phred33-quals', '--bowtie-phred64-quals', and '--bowtie-solex-quals' to avoid confusion
+
+--------------------------------------------------------------------------------------------
+
+RSEM v1.2.6
+
+- Install the latest version of EBSeq from Bioconductor and if fails, try to install EBSeq v1.1.5 locally
+- Fixed a bug in 'rsem-gen-transcript-plots', which makes 'rsem-plot-transcript-wiggles' fail
+
+--------------------------------------------------------------------------------------------
+
RSEM v1.2.5
- Updated EBSeq from v1.1.5 to v1.1.6
projects / rsem.git / blobdiff