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1 #ifndef DECALC_H
2 #define DECALC_H
3 /*
4  *  decalc.h
5  *  Mothur
6  *
7  *  Created by Sarah Westcott on 7/22/09.
8  *  Copyright 2009 Schloss Lab UMASS Amherst. All rights reserved.
9  *
10  */
11
12 #include "mothur.h"
13 #include "sequence.hpp"
14
15 /***********************************************************************/
16
17 //This class was created using the algorythms described in the 
18 // "At Least 1 in 20 16S rRNA Sequence Records Currently Held in the Public Repositories is Estimated To Contain Substantial Anomalies" paper 
19 //by Kevin E. Ashelford 1, Nadia A. Chuzhanova 3, John C. Fry 1, Antonia J. Jones 2 and Andrew J. Weightman 1.
20
21 /***********************************************************************/
22
23 class DeCalculator {
24
25         public:
26         
27                 void trimSeqs(Sequence*, Sequence, map<int, int>&);
28                 vector<float> readFreq();
29                 vector<float> calcFreq(vector<Sequence*>);
30                 
31                 vector<Sequence> findPairs(int, int);
32                 vector<int> findWindows(Sequence*, int, int, int&);
33                 vector<float> calcObserved(Sequence*, Sequence, vector<int>, int);
34                 vector<float>  calcExpected(vector<float>, float);
35                 vector<float>  findQav(vector<int>, int);  
36                 float calcDE(vector<float>, vector<float>);
37                 float calcDist(Sequence*, Sequence, int, int);
38                 float getCoef(vector<float>, vector<float>);
39                 
40         private:
41
42
43 };
44
45 /***********************************************************************/
46
47 #endif