// Marth Lab, Department of Biology, Boston College
// All rights reserved.
// ---------------------------------------------------------------------------
-// Last modified: 19 November 2010 (DB)
+// Last modified: 19 January 2011 (DB)
// ---------------------------------------------------------------------------
// Provides index operations for the BamTools index format (".bti")
// ***************************************************************************
#include <vector>
namespace BamTools {
-
namespace Internal {
+// BTI constants
+const std::string BTI_EXTENSION = ".bti";
+
// individual index offset entry
struct BamToolsIndexEntry {
// ctor
BamToolsIndexEntry(const int32_t& maxEndPosition = 0,
- const int64_t& startOffset = 0,
- const int32_t& startPosition = 0)
- : MaxEndPosition(maxEndPosition)
- , StartOffset(startOffset)
- , StartPosition(startPosition)
+ const int64_t& startOffset = 0,
+ const int32_t& startPosition = 0)
+ : MaxEndPosition(maxEndPosition)
+ , StartOffset(startOffset)
+ , StartPosition(startPosition)
{ }
};
// ctor
BamToolsReferenceEntry(void)
- : HasAlignments(false)
+ : HasAlignments(false)
{ }
};
// else
// do the old thing
enum Version { BTI_1_0 = 1
- , BTI_1_1
- , BTI_1_2
- };
+ , BTI_1_1
+ , BTI_1_2
+ };
// ctor & dtor
public:
- BamToolsIndex(BamTools::BgzfData* bgzf, BamTools::BamReader* reader);
- ~BamToolsIndex(void);
+ BamToolsIndex(void);
+ ~BamToolsIndex(void);
// interface (implements BamIndex virtual methods)
public:
- // creates index data (in-memory) from current reader data
- bool Build(void);
- // returns supported file extension
- const std::string Extension(void) const { return std::string(".bti"); }
- // returns whether reference has alignments or no
- bool HasAlignments(const int& referenceID) const;
- // attempts to use index to jump to region; returns success/fail
- // a "successful" jump indicates no error, but not whether this region has data
- // * thus, the method sets a flag to indicate whether there are alignments
- // available after the jump position
- bool Jump(const BamTools::BamRegion& region, bool* hasAlignmentsInRegion);
+ // creates index data (in-memory) from @reader data
+ bool Build(Internal::BamReaderPrivate* reader);
+ // returns supported file extension
+ const std::string Extension(void) { return BTI_EXTENSION; }
+ // returns whether reference has alignments or no
+ bool HasAlignments(const int& referenceID) const;
+ // attempts to use index to jump to @region in @reader; returns success/fail
+ // a "successful" jump indicates no error, but not whether this region has data
+ // * thus, the method sets a flag to indicate whether there are alignments
+ // available after the jump position
+ bool Jump(Internal::BamReaderPrivate* reader,
+ const BamTools::BamRegion& region,
+ bool *hasAlignmentsInRegion);
+
public:
- // clear all current index offset data in memory
- void ClearAllData(void);
- // return file position after header metadata
- const off_t DataBeginOffset(void) const;
- // return true if all index data is cached
- bool HasFullDataCache(void) const;
- // clears index data from all references except the first
- void KeepOnlyFirstReferenceOffsets(void);
- // load index data for all references, return true if loaded OK
- // @saveData - save data in memory if true, just read & discard if false
- bool LoadAllReferences(bool saveData = true);
- // load first reference from file, return true if loaded OK
- // @saveData - save data in memory if true, just read & discard if false
- bool LoadFirstReference(bool saveData = true);
- // load header data from index file, return true if loaded OK
- bool LoadHeader(void);
- // position file pointer to first reference begin, return true if skipped OK
- bool SkipToFirstReference(void);
- // write index reference data
- bool WriteAllReferences(void);
- // write index header data
- bool WriteHeader(void);
-
- // 'internal' methods
+ // clear all current index offset data in memory
+ void ClearAllData(void);
+ // return file position after header metadata
+ off_t DataBeginOffset(void) const;
+ // return true if all index data is cached
+ bool HasFullDataCache(void) const;
+ // clears index data from all references except the first
+ void KeepOnlyFirstReferenceOffsets(void);
+ // load index data for all references, return true if loaded OK
+ // @saveData - save data in memory if true, just read & discard if false
+ bool LoadAllReferences(bool saveData = true);
+ // load first reference from file, return true if loaded OK
+ // @saveData - save data in memory if true, just read & discard if false
+ bool LoadFirstReference(bool saveData = true);
+ // load header data from index file, return true if loaded OK
+ bool LoadHeader(void);
+ // position file pointer to first reference begin, return true if skipped OK
+ bool SkipToFirstReference(void);
+ // write index reference data
+ bool WriteAllReferences(void);
+ // write index header data
+ bool WriteHeader(void);
+
+ // internal methods
public:
- // -----------------------
- // index file operations
-
- // check index file magic number, return true if OK
- bool CheckMagicNumber(void);
- // check index file version, return true if OK
- bool CheckVersion(void);
- // return true if FILE* is open
- bool IsOpen(void) const;
- // load a single index entry from file, return true if loaded OK
- // @saveData - save data in memory if true, just read & discard if false
- bool LoadIndexEntry(const int& refId, bool saveData = true);
- // load a single reference from file, return true if loaded OK
- // @saveData - save data in memory if true, just read & discard if false
- bool LoadReference(const int& refId, bool saveData = true);
- // loads number of references, return true if loaded OK
- bool LoadReferenceCount(int& numReferences);
- // position file pointer to desired reference begin, return true if skipped OK
- bool SkipToReference(const int& refId);
- // write current reference index data to new index file
- bool WriteReferenceEntry(const BamToolsReferenceEntry& refEntry);
- // write current index offset entry to new index file
- bool WriteIndexEntry(const BamToolsIndexEntry& entry);
-
- // -----------------------
- // index data operations
-
- // clear all index offset data for desired reference
- void ClearReferenceOffsets(const int& refId);
- // calculate BAM file offset for desired region
- // return true if no error (*NOT* equivalent to "has alignments or valid offset")
- // check @hasAlignmentsInRegion to determine this status
- // @region - target region
- // @offset - resulting seek target
- // @hasAlignmentsInRegion - sometimes a file just lacks data in region, this flag indicates that status
- bool GetOffset(const BamRegion& region, int64_t& offset, bool* hasAlignmentsInRegion);
- // returns true if index cache has data for desired reference
- bool IsDataLoaded(const int& refId) const;
- // clears index data from all references except the one specified
- void KeepOnlyReferenceOffsets(const int& refId);
- // saves an index offset entry in memory
- void SaveOffsetEntry(const int& refId, const BamToolsIndexEntry& entry);
- // pre-allocates size for offset vector
- void SetOffsetCount(const int& refId, const int& offsetCount);
- // initializes index data structure to hold @count references
- void SetReferenceCount(const int& count);
+ // -----------------------
+ // index file operations
+
+ // check index file magic number, return true if OK
+ bool CheckMagicNumber(void);
+ // check index file version, return true if OK
+ bool CheckVersion(void);
+ // load a single index entry from file, return true if loaded OK
+ // @saveData - save data in memory if true, just read & discard if false
+ bool LoadIndexEntry(const int& refId, bool saveData = true);
+ // load a single reference from file, return true if loaded OK
+ // @saveData - save data in memory if true, just read & discard if false
+ bool LoadReference(const int& refId, bool saveData = true);
+ // loads number of references, return true if loaded OK
+ bool LoadReferenceCount(int& numReferences);
+ // position file pointer to desired reference begin, return true if skipped OK
+ bool SkipToReference(const int& refId);
+ // write current reference index data to new index file
+ bool WriteReferenceEntry(const BamToolsReferenceEntry& refEntry);
+ // write current index offset entry to new index file
+ bool WriteIndexEntry(const BamToolsIndexEntry& entry);
+
+ // -----------------------
+ // index data operations
+
+ // clear all index offset data for desired reference
+ void ClearReferenceOffsets(const int& refId);
+ // calculate BAM file offset for desired region
+ // return true if no error (*NOT* equivalent to "has alignments or valid offset")
+ // check @hasAlignmentsInRegion to determine this status
+ // @region - target region
+ // @offset - resulting seek target
+ // @hasAlignmentsInRegion - sometimes a file just lacks data in region, this flag indicates that status
+ bool GetOffset(const BamRegion& region, int64_t& offset, bool* hasAlignmentsInRegion);
+ // returns true if index cache has data for desired reference
+ bool IsDataLoaded(const int& refId) const;
+ // clears index data from all references except the one specified
+ void KeepOnlyReferenceOffsets(const int& refId);
+ // saves an index offset entry in memory
+ void SaveOffsetEntry(const int& refId, const BamToolsIndexEntry& entry);
+ // pre-allocates size for offset vector
+ void SetOffsetCount(const int& refId, const int& offsetCount);
+ // initializes index data structure to hold @count references
+ void SetReferenceCount(const int& count);
// data members
private:
- int32_t m_blockSize;
- BamToolsIndexData m_indexData;
- off_t m_dataBeginOffset;
- bool m_hasFullDataCache;
- bool m_isBigEndian;
- int32_t m_inputVersion; // Version is serialized as int
- Version m_outputVersion;
+ int32_t m_blockSize;
+ BamToolsIndexData m_indexData;
+ off_t m_dataBeginOffset;
+ bool m_hasFullDataCache;
+ bool m_isBigEndian;
+ int32_t m_inputVersion; // Version is serialized as int
+ Version m_outputVersion;
};
} // namespace Internal
projects / bamtools.git / blobdiff