#include "tree.h"
+
+/*****************************************************************/
+Tree::Tree() {
+ try {
+
+ globaldata = GlobalData::getInstance();
+ numLeaves = globaldata->gTreemap->getNumSeqs();
+ numNodes = 2*numLeaves - 1;
+
+ tree.resize(numNodes);
+
+ //initialize tree with correct number of nodes, name and group info.
+ for (int i = 0; i < numNodes; i++) {
+ //initialize leaf nodes
+ if (i <= (numLeaves-1)) {
+ tree[i].setName(globaldata->gTreemap->namesOfSeqs[i]);
+ tree[i].setGroup(globaldata->gTreemap->getGroup(globaldata->gTreemap->namesOfSeqs[i]));
+ //set pcount and pGroup for groupname to 1.
+ tree[i].pcount[globaldata->gTreemap->getGroup(globaldata->gTreemap->namesOfSeqs[i])] = 1;
+ tree[i].pGroups[globaldata->gTreemap->getGroup(globaldata->gTreemap->namesOfSeqs[i])] = 1;
+ //Treemap knows name, group and index to speed up search
+ globaldata->gTreemap->setIndex(globaldata->gTreemap->namesOfSeqs[i], i);
+
+ //intialize non leaf nodes
+ }else if (i > (numLeaves-1)) {
+ tree[i].setName("");
+ tree[i].setGroup("");
+ }
+ }
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function Tree. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function Tree. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+
+/*****************************************************************/
+int Tree::getIndex(string searchName) {
+ try {
+ //Treemap knows name, group and index to speed up search
+ // getIndex function will return the vector index or -1 if seq is not found.
+ int index = globaldata->gTreemap->getIndex(searchName);
+ return index;
+
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function getIndex. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function getIndex. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+/*****************************************************************/
+
+void Tree::setIndex(string searchName, int index) {
+ try {
+ //set index in treemap
+ globaldata->gTreemap->setIndex(searchName, index);
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function setIndex. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function setIndex. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+/*****************************************************************/
+void Tree::assembleTree() {
+ try {
+ //build the pGroups in non leaf nodes to be used in the parsimony calcs.
+ for (int i = numLeaves; i < numNodes; i++) {
+ tree[i].pGroups = (mergeGroups(i));
+ tree[i].pcount = (mergeGcounts(i));
+ }
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function assembleTree. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function assembleTree. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+/*****************************************************************/
+void Tree::getCopy(Tree* copy) {
+ try {
+
+ //for each node in the tree copy its info
+ for (int i = 0; i < numNodes; i++) {
+ //copy name
+ tree[i].setName(copy->tree[i].getName());
+
+ //copy group
+ tree[i].setGroup(copy->tree[i].getGroup());
+
+ //copy branch length
+ tree[i].setBranchLength(copy->tree[i].getBranchLength());
+
+ //copy parent
+ tree[i].setParent(copy->tree[i].getParent());
+
+ //copy children
+ tree[i].setChildren(copy->tree[i].getLChild(), copy->tree[i].getRChild());
+
+ //copy index in node and tmap
+ tree[i].setIndex(copy->tree[i].getIndex());
+ setIndex(copy->tree[i].getName(), getIndex(copy->tree[i].getName()));
+
+ //copy pGroups
+ tree[i].pGroups = copy->tree[i].pGroups;
+
+ //copy pcount
+ tree[i].pcount = copy->tree[i].pcount;
+ }
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function getCopy. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function getCopy. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+/*****************************************************************/
+//returns a map with a groupname and the number of times that group was seen in the children
+//for instance if your children are white and black then it would return a map with 2 entries
+// p[white] = 1 and p[black] = 1. Now go up a level and merge that with a node who has p[white] = 1
+//and you get p[white] = 2, p[black] = 1, but you erase the p[black] because you have a p value higher than 1.
+
+map<string, int> Tree::mergeGroups(int i) {
+ try {
+ int lc = tree[i].getLChild();
+ int rc = tree[i].getRChild();
+
+ //set parsimony groups to left child
+ map<string,int> parsimony = tree[lc].pGroups;
+
+ int maxPars = 1;
+
+ //look at right child groups and update maxPars if right child has something higher for that group.
+ for(it=tree[rc].pGroups.begin();it!=tree[rc].pGroups.end();it++){
+ it2 = parsimony.find(it->first);
+ if (it2 != parsimony.end()) {
+ parsimony[it->first]++;
+ }else {
+ parsimony[it->first] = 1;
+ }
+
+ if(parsimony[it->first] > maxPars){
+ maxPars = parsimony[it->first];
+ }
+ }
+
+ // this is true if right child had a greater parsimony for a certain group
+ if(maxPars > 1){
+ //erase all the groups that are only 1 because you found something with 2.
+ for(it=parsimony.begin();it!=parsimony.end();it++){
+ if(it->second == 1){
+ parsimony.erase(it->first);
+// it--;
+ }
+ }
+ //set one remaining groups to 1
+ //so with our above example p[white] = 2 would be left and it would become p[white] = 1
+ for(it=parsimony.begin();it!=parsimony.end();it++){
+ parsimony[it->first] = 1;
+ }
+
+ }
+
+ return parsimony;
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function mergeGroups. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function mergeGroups. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+/*****************************************************************/
+//returns a map with a groupname and the number of times that group was seen in the children
+//for instance if your children are white and black then it would return a map with 2 entries
+// p[white] = 1 and p[black] = 1. Now go up a level and merge that with a node who has p[white] = 1
+//and you get p[white] = 2, p[black] = 1, but you erase the p[black] because you have a p value higher than 1.
+
+map<string, int> Tree::mergeUserGroups(int i, vector<string> g) {
+ try {
+
+ int lc = tree[i].getLChild();
+ int rc = tree[i].getRChild();
+
+ //loop through nodes groups removing the ones the user doesn't want
+ for (it = tree[lc].pGroups.begin(); it != tree[lc].pGroups.end(); it++) {
+ if (inUsersGroups(it->first, g) != true) { tree[lc].pGroups.erase(it->first); }
+ }
+
+ //loop through nodes groups removing the ones the user doesn't want
+ for (it = tree[rc].pGroups.begin(); it != tree[rc].pGroups.end(); it++) {
+ if (inUsersGroups(it->first, g) != true) { tree[rc].pGroups.erase(it->first); }
+ }
+
+ //set parsimony groups to left child
+ map<string,int> parsimony = tree[lc].pGroups;
+
+ int maxPars = 1;
+
+ //look at right child groups and update maxPars if right child has something higher for that group.
+ for(it=tree[rc].pGroups.begin();it!=tree[rc].pGroups.end();it++){
+ it2 = parsimony.find(it->first);
+ if (it2 != parsimony.end()) {
+ parsimony[it->first]++;
+ }else {
+ parsimony[it->first] = 1;
+ }
+
+ if(parsimony[it->first] > maxPars){
+ maxPars = parsimony[it->first];
+ }
+ }
+
+ // this is true if right child had a greater parsimony for a certain group
+ if(maxPars > 1){
+ //erase all the groups that are only 1 because you found something with 2.
+ for(it=parsimony.begin();it!=parsimony.end();it++){
+ if(it->second == 1){
+ parsimony.erase(it->first);
+ }
+ }
+ for(it=parsimony.begin();it!=parsimony.end();it++){
+ parsimony[it->first] = 1;
+ }
+ }
+
+ return parsimony;
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function mergeGroups. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function mergeGroups. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+
+
+/**************************************************************************************************/
+
+map<string,int> Tree::mergeGcounts(int position) {
+ try{
+ map<string,int>::iterator pos;
+
+ int lc = tree[position].getLChild();
+ int rc = tree[position].getRChild();
+
+ map<string,int> sum = tree[lc].pcount;
+
+ for(it=tree[rc].pcount.begin();it!=tree[rc].pcount.end();it++){
+ sum[it->first] += it->second;
+ }
+ return sum;
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function mergeGcounts. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function mergeGcounts. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+/**************************************************************************************************/
+
+void Tree::randomLabels(vector<string> g) {
+ try {
+
+ for(int i = 0; i < numLeaves; i++){
+ int z;
+ //get random index to switch with
+ z = int((float)(i+1) * (float)(rand()) / ((float)RAND_MAX+1.0));
+
+ //you only want to randomize the nodes that are from a group the user wants analyzed, so
+ //if either of the leaf nodes you are about to switch are not in the users groups then you don't want to switch them.
+ bool treez, treei;
+
+ treez = inUsersGroups(tree[z].getGroup(), g);
+ treei = inUsersGroups(tree[i].getGroup(), g);
+
+ if ((treez == true) && (treei == true)) {
+ //switches node i and node z's info.
+ map<string,int> lib_hold = tree[z].pGroups;
+ tree[z].pGroups = (tree[i].pGroups);
+ tree[i].pGroups = (lib_hold);
+
+ string zgroup = tree[z].getGroup();
+ tree[z].setGroup(tree[i].getGroup());
+ tree[i].setGroup(zgroup);
+
+ string zname = tree[z].getName();
+ tree[z].setName(tree[i].getName());
+ tree[i].setName(zname);
+
+ map<string,int> gcount_hold = tree[z].pcount;
+ tree[z].pcount = (tree[i].pcount);
+ tree[i].pcount = (gcount_hold);
+ }
+ }
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function randomLabels. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function randomLabels. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+/**************************************************************************************************/
+
+void Tree::randomLabels(string groupA, string groupB) {
+ try {
+ int numSeqsA = globaldata->gTreemap->seqsPerGroup[groupA];
+ int numSeqsB = globaldata->gTreemap->seqsPerGroup[groupB];
+
+ vector<string> randomGroups(numSeqsA+numSeqsB, groupA);
+ for(int i=numSeqsA;i<randomGroups.size();i++){
+ randomGroups[i] = groupB;
+ }
+ random_shuffle(randomGroups.begin(), randomGroups.end());
+
+ int randomCounter = 0;
+ for(int i=0;i<numLeaves;i++){
+ if(tree[i].getGroup() == groupA || tree[i].getGroup() == groupB){
+ tree[i].setGroup(randomGroups[randomCounter]);
+ tree[i].pcount.clear();
+ tree[i].pcount[randomGroups[randomCounter]] = 1;
+ tree[i].pGroups.clear();
+ tree[i].pGroups[randomGroups[randomCounter]] = 1;
+ randomCounter++;
+ }
+ }
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function randomLabels. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function randomLabels. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+/**************************************************************************************************/
+void Tree::randomBlengths() {
+ try {
+ for(int i=numNodes-1;i>=0;i--){
+ int z = int((float)(i+1) * (float)(rand()) / ((float)RAND_MAX+1.0));
+
+ float bl_hold = tree[z].getBranchLength();
+ tree[z].setBranchLength(tree[i].getBranchLength());
+ tree[i].setBranchLength(bl_hold);
+ }
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function randomBlengths. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function randomBlengths. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+/*************************************************************************************************/
+void Tree::assembleRandomUnifracTree(vector<string> g) {
+ randomLabels(g);
+ assembleTree();
+}
+/*************************************************************************************************/
+void Tree::assembleRandomUnifracTree(string groupA, string groupB) {
+ randomLabels(groupA, groupB);
+ assembleTree();
+}
+
+/*************************************************************************************************/
+//for now it's just random topology but may become random labels as well later that why this is such a simple function now...
+void Tree::assembleRandomTree() {
+ randomTopology();
+ assembleTree();
+}
+/**************************************************************************************************/
+
+void Tree::randomTopology() {
+ try {
+ for(int i=0;i<numNodes;i++){
+ tree[i].setParent(-1);
+ }
+ for(int i=numLeaves;i<numNodes;i++){
+ tree[i].setChildren(-1, -1);
+ }
+
+ for(int i=numLeaves;i<numNodes;i++){
+ int escape =0;
+ int rnd_index1, rnd_index2;
+ while(escape == 0){
+ rnd_index1 = (int)(((double)rand() / (double) RAND_MAX)*i);
+ if(tree[rnd_index1].getParent() == -1){escape = 1;}
+ }
+
+ escape = 0;
+ while(escape == 0){
+ rnd_index2 = (int)(((double)rand() / (double) RAND_MAX)*i);
+ if(rnd_index2 != rnd_index1 && tree[rnd_index2].getParent() == -1){
+ escape = 1;
+ }
+ }
+
+ tree[i].setChildren(rnd_index1,rnd_index2);
+ tree[i].setParent(-1);
+ tree[rnd_index1].setParent(i);
+ tree[rnd_index2].setParent(i);
+ }
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function randomTopology. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function randomTopology. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+
+/*****************************************************************/
+// This prints out the tree in Newick form.
+void Tree::createNewickFile(string f) {
+ try {
+ int root = findRoot();
+ //filename = getRootName(globaldata->getTreeFile()) + "newick";
+ filename = f;
+ openOutputFile(filename, out);
+
+ printBranch(root);
+
+ // you are at the end of the tree
+ out << ";" << endl;
+ out.close();
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function createNewickFile. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function createNewickFile. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+
+/*****************************************************************/
+//This function finds the index of the root node.
+
+int Tree::findRoot() {
+ try {
+ for (int i = 0; i < numNodes; i++) {
+ //you found the root
+ if (tree[i].getParent() == -1) { return i; }
+ }
+ return -1;
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function findRoot. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function findRoot. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+
+/*****************************************************************/
+void Tree::printBranch(int node) {
+ try {
+
+ // you are not a leaf
+ if (tree[node].getLChild() != -1) {
+ out << "(";
+ printBranch(tree[node].getLChild());
+ out << ",";
+ printBranch(tree[node].getRChild());
+ out << ")";
+ }else { //you are a leaf
+ out << tree[node].getGroup() << ":" << tree[node].getBranchLength();
+ }
+
+ }
+ catch(exception& e) {
+ cout << "Standard Error: " << e.what() << " has occurred in the Tree class Function printBranch. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+ catch(...) {
+ cout << "An unknown error has occurred in the Tree class function printBranch. Please contact Pat Schloss at pschloss@microbio.umass.edu." << "\n";
+ exit(1);
+ }
+}
+
+/*****************************************************************/
+
+void Tree::printTree() {
+
+ for(int i=0;i<numNodes;i++){
+ cout << i << '\t';
+ tree[i].printNode();
+ }
+
+}
+
+/*****************************************************************/
+
+
projects / mothur.git / blobdiff