X-Git-Url: https://git.donarmstrong.com/?p=samtools.git;a=blobdiff_plain;f=bam2bcf.h;h=a4d8ca5128319800c91303a022a4e53ac6aea599;hp=94207d092e151f48b64d2380e1e71c1493f2e155;hb=ccb7838cb53bf0ca6917a77f7991d940057c12db;hpb=0bb4884ffb1f4c9485efee763dd63b575f2c1381 diff --git a/bam2bcf.h b/bam2bcf.h index 94207d0..a4d8ca5 100644 --- a/bam2bcf.h +++ b/bam2bcf.h @@ -7,27 +7,39 @@ #define B2B_INDEL_NULL 10000 +#define B2B_FMT_DP 0x1 +#define B2B_FMT_SP 0x2 +#define B2B_FMT_DV 0x4 + typedef struct __bcf_callaux_t { int capQ, min_baseQ; - int openQ, extQ, tandemQ; + int openQ, extQ, tandemQ; // for indels + int min_support; // for collecting indel candidates + double min_frac; // for collecting indel candidates // for internal uses int max_bases; int indel_types[4]; + int maxins, indelreg; + char *inscns; uint16_t *bases; errmod_t *e; + void *rghash; } bcf_callaux_t; typedef struct { - int depth, qsum[4]; + int depth, n_supp, ori_depth, qsum[4]; int anno[16]; float p[25]; + int mvd[3]; // mean variant distance, number of variant reads, average read length } bcf_callret1_t; typedef struct { int a[5]; // alleles: ref, alt, alt2, alt3 int n, n_alleles, shift, ori_ref, unseen; - int anno[16], depth; + int n_supp; // number of supporting non-reference reads + int anno[16], depth, ori_depth; uint8_t *PL; + float vdb; // variant distance bias } bcf_call_t; #ifdef __cplusplus @@ -36,10 +48,12 @@ extern "C" { bcf_callaux_t *bcf_call_init(double theta, int min_baseQ); void bcf_call_destroy(bcf_callaux_t *bca); - int bcf_call_glfgen(int _n, const bam_pileup1_t *pl, int ref_base /*4-bit*/, bcf_callaux_t *bca, bcf_callret1_t *r); + int bcf_call_glfgen(int _n, const bam_pileup1_t *pl, int ref_base, bcf_callaux_t *bca, bcf_callret1_t *r); int bcf_call_combine(int n, const bcf_callret1_t *calls, int ref_base /*4-bit*/, bcf_call_t *call); - int bcf_call2bcf(int tid, int pos, bcf_call_t *bc, bcf1_t *b, bcf_callret1_t *bcr, int is_SP); - int bcf_call_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref); + int bcf_call2bcf(int tid, int pos, bcf_call_t *bc, bcf1_t *b, bcf_callret1_t *bcr, int fmt_flag, + const bcf_callaux_t *bca, const char *ref); + int bcf_call_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref, + const void *rghash); #ifdef __cplusplus }