README.txt for PAML PAML (for Phylogentic Analysis by Maximum Likelihood) contains a few programs for model fitting and phylogenetic tree reconstruction using nucleotide or amino-acid sequence data. ANSI C source codes as well as Win32 and MC OSX excutables are distributed. Win32 executables are in the folder bin. Type, say, bin\codeml to run the codeml program. For UNIX and OS-X systems, go to the src/ folder to compile the programs: "cd src" and then "make". The documentation is in doc/pamlDOC.pdf. The program web page is the following, where the archive can be downloaded: http://abacus.gene.ucl.ac.uk/software/paml.html PAML is distributed free of charge for academic use only. Ziheng Yang Department of Biology Phone: (+44) (0)20 7679 4379 University College London Fax: (+44) (0)20 7679 7096 Darwin Building Email: z.yang @ ucl.ac.uk Gower Street London WC1E 6BT England