general ======= Man pages! I would like to encorporate some domain-specific compression algorithm. Options I know of: * G-SQZ (http://www.tgen.org/research/gsqueez.cfm) : not open source (i.e. not an option) * fqzcomp (http://seqanswers.com/forums/archive/index.php/t-6349.html) * DSRC (http://bioinformatics.oxfordjournals.org/cgi/content/short/27/6/860?rss=1) : Not yet available? * Invent my own. program specific ================ fastq-grep ---------- fastq-kmers ----------- fastq-match ----------- Specifying the score matrix, rather than using a hardcoded. The implementation of the Smith-Waterman algorithm could be more efficient. We might look to Phil Green's cross_match implementation for ideas. An option to return the sequences that match past a certain threshold would be useful. fastq-uniq ----------