polished pairwise alignment code

[biopieces.git] / code_ruby / lib / maasha / align / matches.rb

diff --git a/code_ruby/lib/maasha/align/matches.rb b/code_ruby/lib/maasha/align/matches.rb
index 17f27e2ee982a314125dffe5fdf497e2fac2c39d..009db07cbc225f08a2df4690ade97bb4e557de87 100644 (file)
--- a/code_ruby/lib/maasha/align/matches.rb
+++ b/code_ruby/lib/maasha/align/matches.rb
@@ -22,6 +22,8 @@
 
 # >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>><<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<
 
+require 'maasha/align/match'
+
 # Class containing methods for located all non-redundant Maximally Extended Matches (MEMs)
 # between two strings.
 class Matches
@@ -36,7 +38,7 @@ class Matches
   # between two sequences inside a given search space.
   def matches_find(q_seq, s_seq, q_min, s_min, q_max, s_max, kmer)
     matches   = []
-    redundant = Hash.new { |h, k| h[k] = [] }
+    redundant = {}
 
     s_index = index_seq(s_seq, s_min, s_max, kmer)
 
@@ -48,11 +50,13 @@ class Matches
       s_index[q_oligo].each do |s_pos|
         match = Match.new(q_pos, s_pos, kmer)
         
-        unless match_redundant?(redundant, match)
-          match_expand(match, q_seq, s_seq, q_min, s_min, q_max, s_max)
+        unless redundant[match.q_beg * 1_000_000_000 + match.s_beg]
+          match.expand(q_seq, s_seq, q_min, s_min, q_max, s_max)
           matches << match
 
-          match_redundant_add(redundant, match)
+          (0 ... match.length).each do |j|
+            redundant[(match.q_beg + j) * 1_000_000_000 + match.s_beg + j] = true
+          end
         end
       end
 
@@ -79,80 +83,4 @@ class Matches
 
     index_hash
   end
-
-  # Method to check if a match is redundant.
-  def match_redundant?(redundant, match)
-    redundant[match.q_beg].each do |s_interval|
-      if s_interval.include? match.s_beg and s_interval.include? match.s_end   # TODO test if include? is slow
-        return true
-      end
-    end
-
-    false
-  end
-
-  # Method that adds a match to the redundancy index.
-  def match_redundant_add(redundant, match)
-    (match.q_beg .. match.q_end).each do |q|
-      redundant[q] << (match.s_beg .. match.s_end)
-    end
-  end
-
-  # Method that expands a match as far as possible to the left and right.
-  def match_expand(match, q_seq, s_seq, q_min, s_min, q_max, s_max)
-    match_expand_left(match, q_seq, s_seq, q_min, s_min, q_max, s_max)
-    match_expand_right(match, q_seq, s_seq, q_min, s_min, q_max, s_max)
-
-    match
-  end
-
-  # Method that expands a match as far as possible to the left.
-  def match_expand_left(match, q_seq, s_seq, q_min, s_min, q_max, s_max)
-    while match.q_beg > q_min and
-          match.s_beg > s_min and 
-          q_seq[match.q_beg - 1] == s_seq[match.s_beg - 1]
-      match.q_beg  -= 1
-      match.s_beg  -= 1
-      match.length += 1
-    end
-
-    match
-  end
-
-  # Method that expands a match as far as possible to the right.
-  def match_expand_right(match, q_seq, s_seq, q_min, s_min, q_max, s_max)
-    while match.q_end < q_max and
-          match.s_end < s_max and
-          q_seq[match.q_end + 1] == s_seq[match.s_end + 1]
-      match.length += 1
-    end
-
-    match
-  end
-
-  # Class for containing a match between two sequences q and s.
-  class Match
-    attr_accessor :q_beg, :s_beg, :length, :score
-
-    def initialize(q_beg, s_beg, length, score = 0.0)
-      @q_beg  = q_beg
-      @s_beg  = s_beg
-      @length = length
-      @score  = score
-    end
-
-    def q_end
-      @q_beg + @length - 1
-    end
-
-    def s_end
-      @s_beg + @length - 1
-    end
-
-    def to_s(seq = nil)
-      s = "q: #{@q_beg} #{q_end} s: #{@s_beg} #{s_end} l: #{@length} s: #{@score}"
-      s << " seq: #{seq[@q_beg .. q_end]}" if seq
-      s
-    end
-  end
 end