X-Git-Url: https://git.donarmstrong.com/?a=blobdiff_plain;f=bcftools%2Fprob1.h;h=6f9315565ba1369626d185ac30fcab3502e611d7;hb=125ac895854cf760a04192a257a4279f2c541164;hp=d34a75f56de8e08efa49aa414ef1c5e896ae83a0;hpb=fd187467e3c5f026a4d934c5b0cb68a42939f6e1;p=samtools.git diff --git a/bcftools/prob1.h b/bcftools/prob1.h index d34a75f..6f93155 100644 --- a/bcftools/prob1.h +++ b/bcftools/prob1.h @@ -7,10 +7,18 @@ struct __bcf_p1aux_t; typedef struct __bcf_p1aux_t bcf_p1aux_t; typedef struct { - int rank0; - double f_em, f_exp, f_flat, p_ref; + int rank0, perm_rank; // NB: perm_rank is always set to -1 by bcf_p1_cal() + int ac; // ML alternative allele count + double f_exp, f_flat, p_ref_folded, p_ref, p_var_folded, p_var; + double cil, cih; + double cmp[3], p_chi2, lrt; // used by contrast2() } bcf_p1rst_t; +typedef struct { + double p[4]; + int mq, depth, is_tested, d[4]; +} anno16_t; + #define MC_PTYPE_FULL 1 #define MC_PTYPE_COND2 2 #define MC_PTYPE_FLAT 3 @@ -19,12 +27,20 @@ typedef struct { extern "C" { #endif - bcf_p1aux_t *bcf_p1_init(int n); + bcf_p1aux_t *bcf_p1_init(int n, uint8_t *ploidy); void bcf_p1_init_prior(bcf_p1aux_t *ma, int type, double theta); + void bcf_p1_init_subprior(bcf_p1aux_t *ma, int type, double theta); void bcf_p1_destroy(bcf_p1aux_t *ma); - int bcf_p1_cal(bcf1_t *b, bcf_p1aux_t *ma, bcf_p1rst_t *rst); + void bcf_p1_set_ploidy(bcf1_t *b, bcf_p1aux_t *ma); + int bcf_p1_cal(const bcf1_t *b, int do_contrast, bcf_p1aux_t *ma, bcf_p1rst_t *rst); + int call_multiallelic_gt(bcf1_t *b, bcf_p1aux_t *ma, double threshold, int var_only); int bcf_p1_call_gt(const bcf_p1aux_t *ma, double f0, int k); void bcf_p1_dump_afs(bcf_p1aux_t *ma); + int bcf_p1_read_prior(bcf_p1aux_t *ma, const char *fn); + int bcf_p1_set_n1(bcf_p1aux_t *b, int n1); + void bcf_p1_set_folded(bcf_p1aux_t *p1a); // only effective when set_n1() is not called + + int bcf_em1(const bcf1_t *b, int n1, int flag, double x[10]); #ifdef __cplusplus }