X-Git-Url: https://git.donarmstrong.com/?a=blobdiff_plain;f=bam2bcf.h;h=b2b1825cd59a17a1973b040f722f1efb13ef24f0;hb=28391e5898804ce6b805016d8c676fdf61442eb3;hp=4af080c4753b2070192bec5e04e16174ca5bb5f8;hpb=cb5f44947629a68d16a48d32eef6e42a66e482fe;p=samtools.git diff --git a/bam2bcf.h b/bam2bcf.h index 4af080c..b2b1825 100644 --- a/bam2bcf.h +++ b/bam2bcf.h @@ -7,15 +7,22 @@ #define B2B_INDEL_NULL 10000 +#define B2B_FMT_DP 0x1 +#define B2B_FMT_SP 0x2 +#define B2B_FMT_DV 0x4 + typedef struct __bcf_callaux_t { int capQ, min_baseQ; int openQ, extQ, tandemQ; // for indels - int min_support; // for collecting indel candidates - double min_frac; // for collecting indel candidates + int min_support, max_support; // for collecting indel candidates + double min_frac, max_frac; // for collecting indel candidates + int per_sample_flt; // indel filtering strategy + int *ref_pos, *alt_pos, npos; // for ReadPosBias // for internal uses int max_bases; int indel_types[4]; int maxins, indelreg; + int read_len; char *inscns; uint16_t *bases; errmod_t *e; @@ -23,18 +30,21 @@ typedef struct __bcf_callaux_t { } bcf_callaux_t; typedef struct { - int depth, ori_depth, qsum[4]; - int anno[16]; + int depth, n_supp, ori_depth, qsum[4]; + unsigned int anno[16]; float p[25]; - int mvd[3]; // mean variant distance, number of variant reads, average read length } bcf_callret1_t; typedef struct { int a[5]; // alleles: ref, alt, alt2, alt3 + float qsum[4]; int n, n_alleles, shift, ori_ref, unseen; - int anno[16], depth, ori_depth; + int n_supp; // number of supporting non-reference reads + unsigned int anno[16], depth, ori_depth; uint8_t *PL; float vdb; // variant distance bias + float read_pos_bias; + struct { float avg, var; int dp; } read_pos; } bcf_call_t; #ifdef __cplusplus @@ -44,8 +54,8 @@ extern "C" { bcf_callaux_t *bcf_call_init(double theta, int min_baseQ); void bcf_call_destroy(bcf_callaux_t *bca); int bcf_call_glfgen(int _n, const bam_pileup1_t *pl, int ref_base, bcf_callaux_t *bca, bcf_callret1_t *r); - int bcf_call_combine(int n, const bcf_callret1_t *calls, int ref_base /*4-bit*/, bcf_call_t *call); - int bcf_call2bcf(int tid, int pos, bcf_call_t *bc, bcf1_t *b, bcf_callret1_t *bcr, int is_SP, + int bcf_call_combine(int n, const bcf_callret1_t *calls, bcf_callaux_t *bca, int ref_base /*4-bit*/, bcf_call_t *call); + int bcf_call2bcf(int tid, int pos, bcf_call_t *bc, bcf1_t *b, bcf_callret1_t *bcr, int fmt_flag, const bcf_callaux_t *bca, const char *ref); int bcf_call_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref, const void *rghash);