X-Git-Url: https://git.donarmstrong.com/?a=blobdiff_plain;f=bam2bcf.h;h=8ac6b79abfb60abaeefc29451923ec197c2f6c7a;hb=607d7a0ab79152be4153fa09861cfa889488f2c7;hp=4038f39ba687b900f777b31835aca5204de20b97;hpb=f27c5d351576e00cece3708adcb386da61fe7b7f;p=samtools.git diff --git a/bam2bcf.h b/bam2bcf.h index 4038f39..8ac6b79 100644 --- a/bam2bcf.h +++ b/bam2bcf.h @@ -2,22 +2,46 @@ #define BAM2BCF_H #include +#include "errmod.h" #include "bcftools/bcf.h" -struct __bcf_callaux_t; -typedef struct __bcf_callaux_t bcf_callaux_t; +#define B2B_INDEL_NULL 10000 + +#define B2B_FMT_DP 0x1 +#define B2B_FMT_SP 0x2 +#define B2B_FMT_DV 0x4 + +typedef struct __bcf_callaux_t { + int capQ, min_baseQ; + int openQ, extQ, tandemQ; // for indels + int min_support, max_support; // for collecting indel candidates + double min_frac, max_frac; // for collecting indel candidates + int per_sample_flt; // indel filtering strategy + // for internal uses + int max_bases; + int indel_types[4]; + int maxins, indelreg; + char *inscns; + uint16_t *bases; + errmod_t *e; + void *rghash; +} bcf_callaux_t; typedef struct { - int depth, d[4], ed[4]; - uint64_t sum_Q2; - float p[25], esum[5]; + int depth, n_supp, ori_depth, qsum[4]; + int anno[16]; + float p[25]; + int mvd[3]; // mean variant distance, number of variant reads, average read length } bcf_callret1_t; typedef struct { int a[5]; // alleles: ref, alt, alt2, alt3 + float qsum[4]; int n, n_alleles, shift, ori_ref, unseen; - int d[4], ed[4], depth, rmsQ; + int n_supp; // number of supporting non-reference reads + int anno[16], depth, ori_depth; uint8_t *PL; + float vdb; // variant distance bias } bcf_call_t; #ifdef __cplusplus @@ -26,9 +50,12 @@ extern "C" { bcf_callaux_t *bcf_call_init(double theta, int min_baseQ); void bcf_call_destroy(bcf_callaux_t *bca); - int bcf_call_glfgen(int _n, const bam_pileup1_t *pl, int ref_base /*4-bit*/, bcf_callaux_t *bca, bcf_callret1_t *r); + int bcf_call_glfgen(int _n, const bam_pileup1_t *pl, int ref_base, bcf_callaux_t *bca, bcf_callret1_t *r); int bcf_call_combine(int n, const bcf_callret1_t *calls, int ref_base /*4-bit*/, bcf_call_t *call); - int bcf_call2bcf(int tid, int pos, bcf_call_t *bc, bcf1_t *b); + int bcf_call2bcf(int tid, int pos, bcf_call_t *bc, bcf1_t *b, bcf_callret1_t *bcr, int fmt_flag, + const bcf_callaux_t *bca, const char *ref); + int bcf_call_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref, + const void *rghash); #ifdef __cplusplus }