X-Git-Url: https://git.donarmstrong.com/?a=blobdiff_plain;f=bam2bcf.h;h=8ac6b79abfb60abaeefc29451923ec197c2f6c7a;hb=3a1bd4d97b4d58148b5a7fd845a3b6a023eecbed;hp=570990e4174caec6220c130e0c343dec1d6dd562;hpb=599bea10bc3487a0cbdf505e792a21a13fee2b11;p=samtools.git diff --git a/bam2bcf.h b/bam2bcf.h index 570990e..8ac6b79 100644 --- a/bam2bcf.h +++ b/bam2bcf.h @@ -7,9 +7,16 @@ #define B2B_INDEL_NULL 10000 +#define B2B_FMT_DP 0x1 +#define B2B_FMT_SP 0x2 +#define B2B_FMT_DV 0x4 + typedef struct __bcf_callaux_t { int capQ, min_baseQ; - int openQ, extQ, tandemQ; + int openQ, extQ, tandemQ; // for indels + int min_support, max_support; // for collecting indel candidates + double min_frac, max_frac; // for collecting indel candidates + int per_sample_flt; // indel filtering strategy // for internal uses int max_bases; int indel_types[4]; @@ -17,19 +24,24 @@ typedef struct __bcf_callaux_t { char *inscns; uint16_t *bases; errmod_t *e; + void *rghash; } bcf_callaux_t; typedef struct { - int depth, qsum[4]; + int depth, n_supp, ori_depth, qsum[4]; int anno[16]; float p[25]; + int mvd[3]; // mean variant distance, number of variant reads, average read length } bcf_callret1_t; typedef struct { int a[5]; // alleles: ref, alt, alt2, alt3 + float qsum[4]; int n, n_alleles, shift, ori_ref, unseen; - int anno[16], depth; + int n_supp; // number of supporting non-reference reads + int anno[16], depth, ori_depth; uint8_t *PL; + float vdb; // variant distance bias } bcf_call_t; #ifdef __cplusplus @@ -40,9 +52,10 @@ extern "C" { void bcf_call_destroy(bcf_callaux_t *bca); int bcf_call_glfgen(int _n, const bam_pileup1_t *pl, int ref_base, bcf_callaux_t *bca, bcf_callret1_t *r); int bcf_call_combine(int n, const bcf_callret1_t *calls, int ref_base /*4-bit*/, bcf_call_t *call); - int bcf_call2bcf(int tid, int pos, bcf_call_t *bc, bcf1_t *b, bcf_callret1_t *bcr, int is_SP, + int bcf_call2bcf(int tid, int pos, bcf_call_t *bc, bcf1_t *b, bcf_callret1_t *bcr, int fmt_flag, const bcf_callaux_t *bca, const char *ref); - int bcf_call_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref); + int bcf_call_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref, + const void *rghash); #ifdef __cplusplus }