typedef struct {
int rank0, perm_rank; // NB: perm_rank is always set to -1 by bcf_p1_cal()
- double f_em, f_exp, f_flat, p_ref_folded, p_ref, p_var_folded, p_var;
+ int ac; // ML alternative allele count
+ double f_exp, f_flat, p_ref_folded, p_ref, p_var_folded, p_var;
double cil, cih;
- double cmp[3], p_chi2, f_em2[2]; // used by contrast2()
- double g[3];
+ double cmp[3], p_chi2, lrt; // used by contrast2()
} bcf_p1rst_t;
#define MC_PTYPE_FULL 1
void bcf_p1_init_prior(bcf_p1aux_t *ma, int type, double theta);
void bcf_p1_init_subprior(bcf_p1aux_t *ma, int type, double theta);
void bcf_p1_destroy(bcf_p1aux_t *ma);
- int bcf_p1_cal(const bcf1_t *b, bcf_p1aux_t *ma, bcf_p1rst_t *rst);
+ int bcf_p1_cal(const bcf1_t *b, int do_contrast, bcf_p1aux_t *ma, bcf_p1rst_t *rst);
int bcf_p1_call_gt(const bcf_p1aux_t *ma, double f0, int k);
void bcf_p1_dump_afs(bcf_p1aux_t *ma);
int bcf_p1_read_prior(bcf_p1aux_t *ma, const char *fn);
int bcf_p1_set_n1(bcf_p1aux_t *b, int n1);
void bcf_p1_set_folded(bcf_p1aux_t *p1a); // only effective when set_n1() is not called
+ int bcf_em1(const bcf1_t *b, int n1, int flag, double x[10]);
+
#ifdef __cplusplus
}
#endif