1 [[!meta title="Curriculum Vitæ"]]
5 * [Don Armstrong](http://www.donarmstrong.com/)
6 * <don@donarmstrong.com>
7 * <http://www.donarmstrong.com>
11 * Doctor of Philosophy
12 * 2001-2008 *Cell, Molecular and Developmental Biology*.
13 [University of California at Riverside](http://www.ucr.edu).
14 Dissertation: The Role of membrane Composition in the Activity of
15 Membrane-Associated Signal Transduction Proteins.
17 * 1997-2001 [Biology](http://bio.ucr.edu).
18 [University of California at Riverside](http://www.ucr.edu).
20 Postdoctoral Experience
21 -------------------------
23 ### University of Southern California ###
25 * 2013--Present. Postdoctoral researcher under Chaim O. Jacob.
26 Identifying genes and causal alleles associated with Systemic Lupus
27 Erythematosus using genome-wide association, next-generation
28 sequencing, computational and biochemical approaches.
29 * 2009--2010. Postdoctoral researcher under Florence M. Hofman.
30 Identifying signaling pathways which are responsible for the
31 functional alteration of endothelial cells in glioblastoma
32 multiforme and arteriovenous malformations.
34 ### University of California at Riverside ###
35 * 2010--2012. Postdoctoral researcher under Raphael Zidovetzki.
36 Identifying genes which are associated with Systemic Lupus
37 Erythematosus using prior information and targeted trio-based
42 ### Teaching Assistant ###
43 * 2004--2007. University of California at Riverside. First and second
44 quarter introduction to biology for majors (BIO 5A and 5B).
45 Introduction to Genetics (BIO 102), Human Embryology (CBNS 169).
50 * 2004--Present. [Debian Project](http://www.debian.org), Developer;
51 Technical Committee Member (2010--Present)
53 ### Employment Experience ###
54 * 2002-2003. *Socratech* in Rochester, NY. Bioinformatics researcher:
55 developed new microarray analysis methods for a start-up
56 biotechnology company working on developing treatments for
61 ### In Preparation ###
62 1. *Don L. Armstrong*, Raphael Zidovetzki, and Chaim O Jacob. Novel
63 lupus associated genes discovered in GWAS; two signals explain all
64 HLA SNPs in European Americans. /In preparation/.
66 ## Refereed Publications ##
67 1. Chaim O Jacob, Miriam Eisenstein, Mary C Dinauer, Wenyu Ming,
68 Qiang Liu, Sutha John, Francesco P Quismorio, Andreas Reiff, Barry
69 L Myones, Kenneth M Kaufman, Deborah McCurdy, John B Harley, Earl
70 Silverman, Robert P Kimberly, Timothy J Vyse, Patrick M Gaffney,
71 Kathy L Moser, Marisa Klein-Gitelman, Linda Wagner-Weiner, Carl D
72 Langefeld, *Don L Armstrong*, and Raphael Zidovetzki.
73 Lupus-associated causal mutation in neutrophil cytosolic factor 2
74 (NCF2) brings unique insights to the structure and function of
75 NADPH oxidase. /Proc Natl Acad Sci USA/, 109(2):59--67, Jan 2012.
76 2. *Don L Armstrong*, Omer Markovitch, Raphael Zidovetzki, and Doron
77 Lancet. Replication of simulated prebiotic amphiphile vesicles
78 controlled by experimental lipid physicochemical properties. /Phys
79 Biol/, 8(6):066001, Dec 2011.
81 3. Christopher J Stapleton, *Don L Armstrong*, Raphael Zidovetzki,
82 Charles Y Liu, Steven L Giannotta, and Florence M Hofman.
83 Thrombospondin-1 modulates the angiogenic phenotype of human
84 cerebral arteriovenous malformation endothelial cells.
85 /Neurosurgery/, 68(5):1342--53, May 2011.
87 4. *D L Armstrong*, A Reiff, B L Myones, F P Quismorio, M
88 Klein-Gitelman, D McCurdy, L Wagner-Weiner, E Silverman, J O
89 Ojwang, K M Kaufman, J A Kelly, J T Merrill, J B Harley, S-C Bae, T
90 J Vyse, G S Gilkeson, P M Gaffney, K L Moser, C Putterman, J C
91 Edberg, E E Brown, J Ziegler, C D Langefeld, R Zidovetzki, and C O
92 Jacob. Identification of new SLE-associated genes with a two-step
93 Bayesian study design. /Genes Immun/, 10(5):446--56, Jul 2009.
95 5. Chaim O Jacob, Jiankun Zhu, *Don L Armstrong*, /et al./
96 Identification of IRAK1 as a risk gene with critical role in the
97 pathogenesis of systemic lupus erythematosus. /Proc Natl Acad Sci
98 USA/, 106(15):6256--61, Apr 2009.
100 6. Bahram Namjou, Andrea L Sestak, *Don L Armstrong*, Raphael
101 Zidovetzki, /et al./ High-density genotyping of STAT4 reveals
102 multiple haplotypic associations with systemic lupus erythematosus
103 in different racial groups. /Arthritis Rheum/, 60(4):1085--95, Apr 2009.
105 7. *Don Armstrong* and Raphael Zidovetzki. Amplification of
106 diacylglycerol activation of protein kinase c by cholesterol.
107 /Biophys J/, 94(12):4700--10, Jun 2008.
109 8. *Don L Armstrong*, Chaim O Jacob, and Raphael Zidovetzki.
110 Function2gene: a gene selection tool to increase the power of
111 genetic association studies by utilizing public databases and
112 expert knowledge. *BMC Bioinformatics*, 9:311, 2008.
114 9. Chaim O Jacob, Andreas Reiff, *Don L Armstrong*, Barry L Myones,
115 Earl Silverman, Marisa Klein-Gitelman, Deborah McCurdy, Linda
116 Wagner-Weiner, James J Nocton, Aaron Solomon, and Raphael
117 Zidovetzki. Identification of novel susceptibility genes in
118 childhood-onset systemic lupus erythematosus using a uniquely
119 designed candidate gene pathway platform. /Arthritis Rheum/,
120 56(12):4164--73, Dec 2007.
122 10. Raphael Zidovetzki, Burkhard Rost, /Don L Armstrong/, and Israel
123 Pecht. Transmembrane domains in the functions of fc receptors.
124 /Biophys Chem/, 100(1-3):555--75, 2003.
126 11. *Don L Armstrong*, Dan B Borchardt, and Raphael Zidovetzki.
127 Synergistic perturbation of phosphatidylcholine/sphingomyelin
128 bilayers by diacylglycerol and cholesterol. /Biochem Biophys Res
129 Commun/, 296(4):806--12, Aug 2002.
131 12. Zhenhua Wu, Huang Guo, Nienwen Chow, Jan Sallstrom, Robert D Bell, Rashid
132 Deane, Andrew I Brooks, Suhasini Kanagala, Anna Rubio, Abhay Sagare, Dong
133 Liu, Fang Li, *Don Armstrong*, Thomas Gasiewicz, Raphael Zidovetzki, Xiaomei
134 Song, Florence Hofman, and Berislav V Zlokovic. Role of the meox2 homeobox gene in neurovascular dysfunction in
135 alzheimer disease. /Nat Med/, 11(9):959--65, Sep 2005.
137 13. Rashid Deane, Shi Du Yan, Ram Kumar Submamaryan, Barbara LaRue,
138 Suzana Jovanovic, Elizabeth Hogg, Deborah Welch, Lawrence Manness,
139 Chang Lin, Jin Yu, Hong Zhu, Jorge Ghiso, Blas Frangione, Alan
140 Stern, Ann Marie Schmidt, \textbf{Don L Armstrong}, Bernd Arnold,
141 Birgit Liliensiek, Peter Nawroth, Florence Hofman, Mark Kindy,
142 David Stern, and Berislav Zlokovic. Rage mediates amyloid-beta
143 peptide transport across the blood-brain barrier and accumulation
144 in brain. /Nat Med/, 9(7):907--13, Jul 2003.
146 Selected Presentations
147 ----------------------
148 ### Conference Presentations ###
149 * 2007-06-07. FOCIS 2007. Uniquely designed candidate gene
150 identification platform discovers novel genes in childhood-onset
155 Please e-mail <don@donarmstrong.com> for references