1 [[!meta title="Curriculum Vitæ"]]
5 * [Don Armstrong](http://www.donarmstrong.com/)
6 * <don@donarmstrong.com>
7 * <http://www.donarmstrong.com>
11 * Doctor of Philosophy
12 * 2001-2008 **Cell, Molecular and Developmental Biology**.
13 [University of California at Riverside](http://www.ucr.edu).
14 Dissertation: The Role of membrane Composition in the Activity of
15 Membrane-Associated Signal Transduction Proteins.
17 * 1997-2001 [Biology](http://bio.ucr.edu).
18 [University of California at Riverside](http://www.ucr.edu).
20 Postdoctoral Experience
21 -------------------------
23 ### University of Southern California ###
25 * 2013--Present. Postdoctoral researcher under Chaim O. Jacob.
26 Identifying genes and causal alleles associated with Systemic Lupus
27 Erythematosus using genome-wide association, next-generation
28 sequencing, computational and biochemical approaches.
29 * 2009--2010. Postdoctoral researcher under Florence M. Hofman.
30 Identifying signaling pathways which are responsible for the
31 functional alteration of endothelial cells in glioblastoma
32 multiforme and arteriovenous malformations.
34 ### University of California at Riverside ###
35 * 2010--2012. Postdoctoral researcher under Raphael Zidovetzki.
36 Identifying genes which are associated with Systemic Lupus
37 Erythematosus using prior information and targeted trio-based
42 ### Teaching Assistant ###
43 * 2004--2007. University of California at Riverside. First and second
44 quarter introduction to biology for majors (BIO 5A and 5B).
45 Introduction to Genetics (BIO 102), Human Embryology (CBNS 169).
50 * 2004--Present. [Debian Project](http://www.debian.org), Developer;
51 Technical Committee Member (2010--Present)
53 ### Employment Experience ###
54 * 2002-2003. **Socratech** in Rochester, NY. Bioinformatics researcher:
55 developed new microarray analysis methods for a start-up
56 biotechnology company working on developing treatments for
61 ## Refereed Publications ##
62 1. **Don L. Armstrong**, Raphael Zidovetzki, and Chaim O Jacob. Novel
63 lupus associated genes discovered in GWAS; two signals explain all
64 HLA SNPs in European Americans. *Genes Immun*, In press.
66 2. Chaim O Jacob, Miriam Eisenstein, Mary C Dinauer, Wenyu Ming,
67 Qiang Liu, Sutha John, Francesco P Quismorio, Andreas Reiff, Barry
68 L Myones, Kenneth M Kaufman, Deborah McCurdy, John B Harley, Earl
69 Silverman, Robert P Kimberly, Timothy J Vyse, Patrick M Gaffney,
70 Kathy L Moser, Marisa Klein-Gitelman, Linda Wagner-Weiner, Carl D
71 Langefeld, **Don L Armstrong**, and Raphael Zidovetzki.
72 Lupus-associated causal mutation in neutrophil cytosolic factor 2
73 (NCF2) brings unique insights to the structure and function of
74 NADPH oxidase. *Proc Natl Acad Sci USA*, 109(2):59--67, Jan 2012.
75 3. **Don L Armstrong**, Omer Markovitch, Raphael Zidovetzki, and Doron
76 Lancet. Replication of simulated prebiotic amphiphile vesicles
77 controlled by experimental lipid physicochemical properties. *Phys
78 Biol*, 8(6):066001, Dec 2011.
80 4. Christopher J Stapleton, **Don L Armstrong**, Raphael Zidovetzki,
81 Charles Y Liu, Steven L Giannotta, and Florence M Hofman.
82 Thrombospondin-1 modulates the angiogenic phenotype of human
83 cerebral arteriovenous malformation endothelial cells.
84 *Neurosurgery*, 68(5):1342--53, May 2011.
86 5. **D L Armstrong**, A Reiff, B L Myones, F P Quismorio, M
87 Klein-Gitelman, D McCurdy, L Wagner-Weiner, E Silverman, J O
88 Ojwang, K M Kaufman, J A Kelly, J T Merrill, J B Harley, S-C Bae, T
89 J Vyse, G S Gilkeson, P M Gaffney, K L Moser, C Putterman, J C
90 Edberg, E E Brown, J Ziegler, C D Langefeld, R Zidovetzki, and C O
91 Jacob. Identification of new SLE-associated genes with a two-step
92 Bayesian study design. *Genes Immun*, 10(5):446--56, Jul 2009.
94 6. Chaim O Jacob, Jiankun Zhu, **Don L Armstrong**, *et al.*
95 Identification of IRAK1 as a risk gene with critical role in the
96 pathogenesis of systemic lupus erythematosus. *Proc Natl Acad Sci
97 USA*, 106(15):6256--61, Apr 2009.
99 7. Bahram Namjou, Andrea L Sestak, **Don L Armstrong**, Raphael
100 Zidovetzki, *et al.* High-density genotyping of STAT4 reveals
101 multiple haplotypic associations with systemic lupus erythematosus
102 in different racial groups. *Arthritis Rheum*, 60(4):1085--95, Apr 2009.
104 8. **Don Armstrong** and Raphael Zidovetzki. Amplification of
105 diacylglycerol activation of protein kinase c by cholesterol.
106 *Biophys J*, 94(12):4700--10, Jun 2008.
108 9. **Don L Armstrong**, Chaim O Jacob, and Raphael Zidovetzki.
109 Function2gene: a gene selection tool to increase the power of
110 genetic association studies by utilizing public databases and
111 expert knowledge. **BMC Bioinformatics**, 9:311, 2008.
113 10. Chaim O Jacob, Andreas Reiff, **Don L Armstrong**, Barry L Myones,
114 Earl Silverman, Marisa Klein-Gitelman, Deborah McCurdy, Linda
115 Wagner-Weiner, James J Nocton, Aaron Solomon, and Raphael
116 Zidovetzki. Identification of novel susceptibility genes in
117 childhood-onset systemic lupus erythematosus using a uniquely
118 designed candidate gene pathway platform. *Arthritis Rheum*,
119 56(12):4164--73, Dec 2007.
121 11. Raphael Zidovetzki, Burkhard Rost, *Don L Armstrong*, and Israel
122 Pecht. Transmembrane domains in the functions of fc receptors.
123 *Biophys Chem*, 100(1-3):555--75, 2003.
125 12. **Don L Armstrong**, Dan B Borchardt, and Raphael Zidovetzki.
126 Synergistic perturbation of phosphatidylcholine/sphingomyelin
127 bilayers by diacylglycerol and cholesterol. *Biochem Biophys Res
128 Commun*, 296(4):806--12, Aug 2002.
130 13. Zhenhua Wu, Huang Guo, Nienwen Chow, Jan Sallstrom, Robert D Bell, Rashid
131 Deane, Andrew I Brooks, Suhasini Kanagala, Anna Rubio, Abhay Sagare, Dong
132 Liu, Fang Li, **Don Armstrong**, Thomas Gasiewicz, Raphael Zidovetzki, Xiaomei
133 Song, Florence Hofman, and Berislav V Zlokovic. Role of the meox2 homeobox gene in neurovascular dysfunction in
134 alzheimer disease. *Nat Med*, 11(9):959--65, Sep 2005.
136 14. Rashid Deane, Shi Du Yan, Ram Kumar Submamaryan, Barbara LaRue,
137 Suzana Jovanovic, Elizabeth Hogg, Deborah Welch, Lawrence Manness,
138 Chang Lin, Jin Yu, Hong Zhu, Jorge Ghiso, Blas Frangione, Alan
139 Stern, Ann Marie Schmidt, **Don L Armstrong**, Bernd Arnold,
140 Birgit Liliensiek, Peter Nawroth, Florence Hofman, Mark Kindy,
141 David Stern, and Berislav Zlokovic. Rage mediates amyloid-beta peptide transport across the blood-brain
142 barrier and accumulation in brain. *Nat Med*, 9(7):907--13, Jul 2003.
144 Selected Presentations
145 ----------------------
146 ### Conference Presentations ###
147 * 2007-06-07. FOCIS 2007. Uniquely designed candidate gene
148 identification platform discovers novel genes in childhood-onset
153 Please e-mail <don@donarmstrong.com> for references